Glanzmann's Thrombasthenia Complicating Pregnancy.

Management of Pregnancy in a Chilean Patient with Congenital Deficiency of Factor VII and Glanzmann's Thrombasthenia Variant

Patients with inherited bleeding disorders are rare in obstetric practice but present with prolonged bleeding even after minor invasive procedures. They require a combined approach with obstetric and hematological management of each case, including the neonatal management of a possibly affected fetus. We present the case of a pregnancy in a patient with combined Factor VII deficiency and Glanzm...

Dental Considerations in the Management of Glanzmann’s Thrombasthenia

Glanzmann's thrombasthenia, is one of the rarest congenital, genetically inherited platelet disorder. It has an incidence of about 1:1,000,000, but is more common in populations with increased consanguinity. Glanzmann's thrombasthenia is characterized by deficiency or dysfunction of glycoprotein (GP) lib and Ilia, which are the receptors of fibrinogen. Both sexes are equally affected. Typical m...

Glanzmann's thrombasthenia: report of a case and review of the literature.

Glanzmann's thrombasthenia is a rare congenital bleeding disorder. Patients usually present with mucocutaneous bleeding and excessive bleeding associated with trauma and/or surgery. Patients have an increased bleeding time and a normal platelet count with abnormal platelet function assays. Genetically, Glanzmann's thrombasthenia is associated with mutations in the genes which encode for glycopr...

Possible thrombosthenin defect in Glanzmann's thrombasthenia.

Renal embolisation in Glanzmann's thrombasthenia.

The patient, a 58-year-old woman, had suffered from excessive bleeding since early childhood. The coagulation studies were diagnostic of Glanzmann's thrombasthenia with diminished platelet aggregation in response to ristocetin (table). She was admitted to hospital because of intractable haematuria for which no cause could be established. There were no signs of urinary tract infection or stones....